Vargas, who joined the club in January, netted for the Liga MX outfit for the first time in the 1-1 draw on Wednesday.
WATCH: Vargas nets for Tigres
The Chile international’s 25-yard effort for the home side was canceled out by Matias Britos just after the hour mark.
The New York Red Bulls were held to a 1-1 draw at home against the Vancouver Whitecaps.
Kekuta Manneh had given Vancouver a 39th-minute lead with a header, but that advantage should have disappeared shortly after the break.
The home side was awarded a penalty but Sacha Kljestan’s Panenka attempt was kept out by David Ousted.
Bradley Wright-Phillips leveled for the Red Bulls in the 62nd minute and Vancouver was dealt a further blow when Cristian Techera saw red for a rash challenge.
The second legs of the ties will be played next month.
